- Course title: Behavioural Genetics
- Responsible person and department
|Dr. Enikő Kubinyi,
|senior research fellow||Department of Ethology, ELTE|
|Dr. Enikő Kubinyi||senior research fellow||Department of Ethology, ELTE|
- Prior requirements and knowledge
No prior knowledge is expected
- Obligatory/Recommended studies
- Detailed topics of the course
- Introduction to behavioural genetics
Historical perspective, Mendel’s laws of heredity, exceptions to Mendel’s law, complex traits, multiple-gene inheritance, the biological basis (DNA, chromosomes).
- Animal models in behavioural genetics
Quantitative genetic experiments, identifying genes and gene functions, creating mutations.
- Nature, nurture, and human behaviour
Adoption and twin designs, heritability, estimating genetic and environmental influences (shared and non-shared).
- The interplay between genes and environment
Genotype-environment correlation and interaction, methods of detecting.
- Identifying genes
Mutations, polymorphisms, single-gene and complex disorders, candidate gene method, GWAS.
- Gene expression and epigenetics
Transcriptome, RNA microarrays, sequence-based methods, proteome.
- The genetic background of complex behavioural traits: cognitive abilities
General and specific cognitive abilities, school achievement, neurocognitive measures.
- Cognitive disabilities
Phenylketonuria, Fragile X syndrome, Rett syndrome, Down syndrome, sex chromosome abnormalities, small chromosomal deletions, reading and mathematical disabilities.
- Personality and personality disorders
Schizotypal personality disorders, obsessive-compulsive personality disorder, antisocial personality disorder and criminal behavior.
- Developmental and adult psychopathology
Schizophrenia (twin studies, twin studies), mood and anxiety disorders, co-occurrence of disorders, autism, attention-deficit and hyperactivity disorder, disruptive behaviour disorders.
- Substance use disorders
Alcohol and nicotine dependence, other drugs.
- Health psychology
Obesity, subjective well-being and health, genetic counselling.
Cognitive aging, general and specific cognitive abilities, dementia, longevity.
- The future of behavioural genetics
Quantitative genetics, molecular genetics.
- Mode of teaching
After a short introduction about the topic, students provide presentations based on published papers.
This is a 4 days course in the exam period. Students are required to read chapters of the recommended books or other materials, give two oral presentations, and take a written test. Instead of the two oral presentations writing a popular science article is an alternative option.
- Consultation possibilities:
1 hour weekly
- Notes, books, and recommended literature
Knopik, V. S., Neiderhiser, J., DeFries, J. C., Plomin, R. (2016). Behavioral genetics. (7th ed.) New York: Worth Publishers